Human HSPB8 protein (Recombinant) (C-His) (STJP014725)
SPECIFICATIONS
HostE.coli
ConjugationUnconjugated
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human HSPB8-C-His protein was developed from e.coli and has a target region of C-His. For use in research applications. |
| Applications | ELISA/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Formulation | Supplied as a 0.22 Mu m filtered solution in 20mM PB, 150mM NaCl, 5mM EDTA, pH 7.4. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8ยฐC for one week. Store at-20 to-80ยฐC for twelve months from the date of receipt. |
| Endotoxin | < 1 EU/ยตg as determined by LAL test. |
Target Information
| Gene Symbol | HSPB8 |
| Gene ID | 26353 |
| Uniprot ID | HSPB8_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Met1-Thr196 |
Additional Info
| Function | Involved in the chaperone-assisted selective autophagy (CASA), a crucial process for protein quality control, particularly in mechanical strained cells and tissues such as muscle. Displays temperature-dependent chaperone activity. |
| Protein Name | Heat Shock Protein Beta-8Hspb8Alpha-Crystallin C ChainE2-Induced Gene 1 ProteinHeat Shock Protein Family B Member 8Protein Kinase H11Small Stress Protein-Like Protein Hsp22 |
| Database Links | Reactome: R-HSA-3371571 |
| Cellular Localisation | CytoplasmNucleusTranslocates To Nuclear Foci During Heat Shock |
| Alternative Protein Names | Heat Shock Protein Beta-8 proteinHspb8 proteinAlpha-Crystallin C Chain proteinE2-Induced Gene 1 Protein proteinHeat Shock Protein Family B Member 8 proteinProtein Kinase H11 proteinSmall Stress Protein-Like Protein Hsp22 proteinHSPB8 proteinCRYAC proteinE2IG1 proteinHSP22 proteinPP1629 protein |
Information sourced from Uniprot.org