| Function | Interacts with HSP70 and can stimulate its ATPase activity. Stimulates the association between HSC70 and HIP. Negatively regulates heat shock-induced HSF1 transcriptional activity during the attenuation and recovery phase period of the heat shock response. Stimulates ATP hydrolysis and the folding of unfolded proteins mediated by HSPA1A/B (in vitro). |
| Protein Name | Dnaj Homolog Subfamily B Member 1Dnaj Protein Homolog 1Heat Shock 40 Kda Protein 1Hsp40Heat Shock Protein 40Human Dnaj Protein 1Hdj-1 |
| Database Links | Reactome: R-HSA-3371453Reactome: R-HSA-3371497Reactome: R-HSA-3371568Reactome: R-HSA-3371571Reactome: R-HSA-5687128 |
| Cellular Localisation | CytoplasmNucleusNucleolusTranslocates Rapidly From The Cytoplasm To The NucleusAnd Especially To The NucleoliUpon Heat Shock |
| Alternative Protein Names | Dnaj Homolog Subfamily B Member 1 proteinDnaj Protein Homolog 1 proteinHeat Shock 40 Kda Protein 1 proteinHsp40 proteinHeat Shock Protein 40 proteinHuman Dnaj Protein 1 proteinHdj-1 proteinDNAJB1 proteinDNAJ1 proteinHDJ1 proteinHSPF1 protein |
Information sourced from Uniprot.org
