Human HSD17b3 (17-Beta-Hydroxysteroid Dehydrogenase Type 3) Sandwich ELISA Kit Ready-To-Use Kit (STJE0015914)
SPECIFICATIONS
General Information
| Short Description | This HSD17b3 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human serum, plasma, tissue homogenates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Human |
| Sensitivity | 6.4pg/mL |
| Detection Limit | 15.6-1000pg/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 3 hrs |
Target Information
| Gene Symbol | HSD17B3 |
| Gene ID | 3293 |
| Uniprot ID | DHB3_HUMAN |
| Immunogen Region | Ready-To-Use |
| Sample Type | serum, plasma, tissue homogenates or other biological fluids. |
Additional Info
| Tissue Specificity | Testis. |
| Post Translational Modifications | |
| Function | Catalyzes the conversion of 17-oxosteroids to 17beta-hydroxysteroids. Favors the reduction of androstenedione to testosterone. Testosterone is the key androgen driving male development and function. Uses NADPH while the two other EDH17B enzymes use NADH. Androgens such as epiandrosterone, dehydroepiandrosterone, androsterone and androstanedione are accepted as substrates and reduced at C-17. Can reduce 11-ketoandrostenedione as well as 11beta-hydroxyandrostenedione at C-17 to the respective testosterone forms. |
| Protein Name | 17-Beta-Hydroxysteroid Dehydrogenase Type 317-Beta-Hsd 3Estradiol 17-Beta-Dehydrogenase 2Short Chain Dehydrogenase/Reductase Family 12c Member 2Testicular 17-Beta-Hydroxysteroid DehydrogenaseTestosterone 17-Beta-Dehydrogenase 3 |
| Database Links | Reactome: R-HSA-193048Reactome: R-HSA-75876 |
| Cellular Localisation | Endoplasmic Reticulum |
| Alternative ELISA Names | 17-Beta-Hydroxysteroid Dehydrogenase Type 3 ELISA kit17-Beta-Hsd 3 ELISA kitEstradiol 17-Beta-Dehydrogenase 2 ELISA kitShort Chain Dehydrogenase/Reductase Family 12c Member 2 ELISA kitTesticular 17-Beta-Hydroxysteroid Dehydrogenase ELISA kitTestosterone 17-Beta-Dehydrogenase 3 ELISA kitHSD17B3 ELISA kitEDH17B3 ELISA kitSDR12C2 ELISA kit |
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Information sourced from Uniprot.org