Human HS3ST1 protein (Recombinant) (His-Tag) (STJP018423)

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STJP018423
£134.50 - £738.50
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Short Description :Recombinant-Human HS3ST1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications:SDS-PAGE
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Concentration:0.25 mg/mL
Formulation:Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 40% Glycerol, 2mM DTT
Storage Instruction:For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol:HS3ST1
Gene ID:9957
Uniprot ID:HS3S1_HUMAN
Accession Number:NP_005105
Immunogen:Human
Immunogen Region:21-307aa
Immunogen Sequence:MGSSHHHHHH SSGLVPRGSH MGSRPAELGQ QELLRKAGTL QDDVRDGVAP NGSAQQLPQT IIIGVRKGGT RALLEMLSLH PDVAAAENEV HFFDWEEHYS HGLGWYLSQM PFSWPHQLTV EKTPAYFTSP KVPERVYSMN PSIRLLLILR DPSERVLSDY TQVFYNHMQK HKPYPSIEEF LVRDGRLNVD YKALNRSLYH VHMQNWLRFF PLRHIHIVDG DRLIRDPF
Tissue Specificity Highly expressed in the brain and kidney and weakly expressed in the heart, lung and placenta.
Function Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) to catalyze the transfer of a sulfo group to position 3 of glucosamine residues in heparan. Catalyzes the rate limiting step in the biosynthesis of heparan sulfate (HSact). This modification is a crucial step in the biosynthesis of anticoagulant heparan sulfate as it completes the structure of the antithrombin pentasaccharide binding site.
Protein Name Heparan Sulfate Glucosamine 3-O-Sulfotransferase 1
Heparan Sulfate D-Glucosaminyl 3-O-Sulfotransferase 1
3-Ost-1
Heparan Sulfate 3-O-Sulfotransferase 1
H3-Ost-1
Database Links Reactome: R-HSA-2022928
Cellular Localisation Golgi Apparatus Lumen
Alternative Protein Names Heparan Sulfate Glucosamine 3-O-Sulfotransferase 1 protein
Heparan Sulfate D-Glucosaminyl 3-O-Sulfotransferase 1 protein
3-Ost-1 protein
Heparan Sulfate 3-O-Sulfotransferase 1 protein
H3-Ost-1 protein
HS3ST1 protein
3OST protein
3OST1 protein

Information sourced from Uniprot.org