Human HS2ST1 protein (Recombinant) (N-His) (STJP005627)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human HS2ST1-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | HS2ST1 |
| Gene ID | 9653 |
| Uniprot ID | HS2ST_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Asn29-Trp229 |
Additional Info
| Function | Catalyzes the transfer of a sulfo group from 3'-phospho-5'-adenylyl sulfate (PAPS) to the 2-OH position of iduronic acid (IdoA) or glucuronic acid (GlcA) within the heparan sulfate (HS) chain and participates in HS biosynthesis. Required for metanephric development of kidney formation, suggesting that 2-O-sulfation within HS is essential for signaling between ureteric bud and metanephric mesenchyme. |
| Protein Name | Heparan Sulfate 2-O-Sulfotransferase 12-O-Sulfotransferase2-Ost2ostHs 2-O-SulfotransferaseHeparan Sulfate 2-Sulfotransferase |
| Database Links | Reactome: R-HSA-2022928 |
| Cellular Localisation | Golgi Apparatus MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Protein Names | Heparan Sulfate 2-O-Sulfotransferase 1 protein2-O-Sulfotransferase protein2-Ost protein2ost proteinHs 2-O-Sulfotransferase proteinHeparan Sulfate 2-Sulfotransferase proteinHS2ST1 proteinHS2ST proteinKIAA0448 protein |
Information sourced from Uniprot.org