Human HPS6 protein (Recombinant) (N-His-SUMO) (STJP008768)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human HPS6-N-His-SUMO protein was developed from e.coli for the region N-His-SUMO. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | HPS6 |
| Gene ID | 79803 |
| Uniprot ID | HPS6_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Thr371-Met454 |
Additional Info
| Function | May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules. Acts as a cargo adapter for the dynein-dynactin motor complex to mediate the transport of lysosomes from the cell periphery to the perinuclear region. Facilitates retrograde lysosomal trafficking by linking the motor complex to lysosomes, and perinuclear positioning of lysosomes is crucial for the delivery of endocytic cargos to lysosomes, for lysosome maturation and functioning. |
| Protein Name | Bloc-2 Complex Member Hps6Hermansky-Pudlak Syndrome 6 ProteinRuby-Eye Protein HomologRu |
| Database Links | |
| Cellular Localisation | Microsome MembraneCytoplasmCytosolEarly Endosome MembraneLysosome Membrane |
| Alternative Protein Names | Bloc-2 Complex Member Hps6 proteinHermansky-Pudlak Syndrome 6 Protein proteinRuby-Eye Protein Homolog proteinRu proteinHPS6 protein |
Information sourced from Uniprot.org