Human HO-2/HMOX2 protein (Recombinant) (No-Tag) (STJP016612)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human HO-2/HMOX2-No-Tag protein was developed from e.coli and has a target region of No-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in phosphate-Buffered Saline (pH 7.4) containing 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | HMOX2 |
| Gene ID | 3163 |
| Uniprot ID | HMOX2_HUMAN |
| Accession Number | NP_002125.3 |
| Immunogen | Human |
| Immunogen Region | 1-264aa |
| Immunogen Sequence | MSAEVETSEG VDESEKKNSG ALEKENQMRM ADLSELLKEG TKEAHDRAEN TQFVKDFLKG NIKKELFKLA TTALYFTYSA LEEEMERNKD HPAFAPLYFP MELHRKEALT KDMEYFFGEN WEEQVQCPKA AQKYVERIHY IGQNEPELLV AHAYTRYMGD LSGGQVLKKV AQRALKLPST GEGTQFYLFE NVDNAQQFKQ LYRARMNALD LNMKTKERIV EEANKAFE |
Additional Info
| Post Translational Modifications | A soluble form arises by proteolytic removal of the membrane anchor. S-nitrosylated by BLVRB. |
| Function | Heme oxygenase 2: Catalyzes the oxidative cleavage of heme at the alpha-methene bridge carbon, released as carbon monoxide (CO), to generate biliverdin IXalpha, while releasing the central heme iron chelate as ferrous iron. Heme oxygenase 2 soluble form: Catalyzes the oxidative cleavage of heme at the alpha-methene bridge carbon, released as carbon monoxide (CO), to generate biliverdin IXalpha, while releasing the central heme iron chelate as ferrous iron. |
| Protein Name | Heme Oxygenase 2Ho-2 Cleaved Into - Heme Oxygenase 2 Soluble Form |
| Database Links | Reactome: R-HSA-189483Reactome: R-HSA-6798695Reactome: R-HSA-8980692Reactome: R-HSA-917937Reactome: R-HSA-9707564 |
| Cellular Localisation | Microsome MembraneSingle-Pass Type Iv Membrane ProteinCytoplasmic SideEndoplasmic Reticulum Membrane |
| Alternative Protein Names | Heme Oxygenase 2 proteinHo-2 Cleaved Into - Heme Oxygenase 2 Soluble Form proteinHMOX2 proteinHO2 protein |
Information sourced from Uniprot.org