Human HNRNPAB protein (Recombinant) (His-Tag) (STJP018474)

SPECIFICATIONS
HostE.coli
ImmunogenHuman
STJP018474
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General Information

Short DescriptionRecombinant-Human HNRNPAB-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
ApplicationsSDS-PAGE
HostE.coli
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

Concentration0.25 mg/mL
FormulationLiquid in phosphate-Buffered Saline (pH 7.4) containing 30% Glycerol, 1mM DTT
Storage InstructionFor short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolHNRNPAB
Gene ID3182
Uniprot IDROAA_HUMAN
Accession NumberNP_004490
ImmunogenHuman
Immunogen Region1-285aa
Immunogen SequenceMGSSHHHHHH SSGLVPRGSH MGSMSEAGEE QPMETTGATE NGHEAVPEGE SPAGAGTGAA AGAGGATAAP PSGNQNGAEG DQINASKNEE DAGKMFVGGL SWDTSKKDLK DYFTKFGEVV DCTIKMDPNT GRSRGFGFIL FKDAASVEKV LDQKEHRLDG RVIDPKKAMA MKKDPVKKIF VGGLNPEATE EKIREYFGEF GEIEAIELPM DPKLNKRRGF VFITFKEE

Additional Info

Tissue Specificity Ubiquitous.
Post Translational Modifications Dimethylation at Arg-322 is probably asymmetric.
Function Binds single-stranded RNA. Has a high affinity for G-rich and U-rich regions of hnRNA. Also binds to APOB mRNA transcripts around the RNA editing site.
Protein Name Heterogeneous Nuclear Ribonucleoprotein A/B
Hnrnp A/B
Apobec1-Binding Protein 1
Abbp-1
Database Links
Cellular Localisation Nucleus
Cytoplasm
Localized In Cytoplasmic Mrnp Granules Containing Untranslated Mrnas
Alternative Protein Names Heterogeneous Nuclear Ribonucleoprotein A/B protein
Hnrnp A/B protein
Apobec1-Binding Protein 1 protein
Abbp-1 protein
HNRNPAB protein
ABBP1 protein
HNRPAB protein

Information sourced from Uniprot.org

Citations

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