Human HNF4A protein (Recombinant) (N-His) (STJP004699)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human HNF4A-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | HNF4A |
| Gene ID | 3172 |
| Uniprot ID | HNF4A_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Gln131-Ser330 |
Additional Info
| Function | Transcriptional regulator which controls the expression of hepatic genes during the transition of endodermal cells to hepatic progenitor cells, facilitating the recruitment of RNA pol II to the promoters of target genes. Activates the transcription of CYP2C38. Represses the CLOCK-BMAL1 transcriptional activity and is essential for circadian rhythm maintenance and period regulation in the liver and colon cells. |
| Protein Name | Hepatocyte Nuclear Factor 4-AlphaHnf-4-AlphaNuclear Receptor Subfamily 2 Group A Member 1Transcription Factor 14Tcf-14Transcription Factor Hnf-4 |
| Database Links | Reactome: R-HSA-210745Reactome: R-HSA-383280Reactome: R-HSA-9831926 |
| Cellular Localisation | Nucleus |
| Alternative Protein Names | Hepatocyte Nuclear Factor 4-Alpha proteinHnf-4-Alpha proteinNuclear Receptor Subfamily 2 Group A Member 1 proteinTranscription Factor 14 proteinTcf-14 proteinTranscription Factor Hnf-4 proteinHNF4A proteinHNF4 proteinNR2A1 proteinTCF14 protein |
Information sourced from Uniprot.org