| Tissue Specificity | Expressed in liver, kidney, prostate, testis and uterus. |
| Function | Nicotinic acid adenine dinucleotide phosphate (NAADP) binding protein required for NAADP-evoked intracellular calcium release. Confers NAADP-sensitivity to the two pore channels (TPCs) complex. Enables NAADP to activate Ca(2+) release from the endoplasmic reticulum through ryanodine receptors. (Microbial infection) Involved in the endolysosomal trafficking of human coronavirus SARS-CoV-2. |
| Protein Name | Jupiter Microtubule Associated Homolog 2Hematological And Neurological Expressed 1-Like ProteinHn1-Like Protein |
| Database Links | |
| Cellular Localisation | CytoplasmNucleusColocalizes With Type 1 Ryanodine Receptor (Ryr1) |
| Alternative Protein Names | Jupiter Microtubule Associated Homolog 2 proteinHematological And Neurological Expressed 1-Like Protein proteinHn1-Like Protein proteinJPT2 proteinC16orf34 proteinHN1L proteinL11 protein |
Information sourced from Uniprot.org