Human HN1L protein (Recombinant) (His-Tag) (STJP018041)

SKU:
STJP018041
£134.50 - £738.50
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Host: E.coli
Applications: SDS-PAGE
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human HN1L-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Formulation: Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% Glycerol
Concentration: 1 mg/mL
Storage Instruction: For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol: JPT2
Gene ID: 90861
Uniprot ID: JUPI2_HUMAN
Immunogen Region: 1-190aa
Accession Number: NP_653171.1
Immunogen: Human
Immunogen Sequence: MFQVPDS EGGRAGSRAM KPPGGESSNL FGSPEEATPS SRPNRMASNI FGPTEEPQNI PKRTNPPGGK GSGIFDESTP VQTRQHLNPP GGKTSDIFGS PVTATSRLAH PNKPKDHVFL CEGEEPKSDL KAARSIPAGA EPGEKGSARK AGPAKEQEPM PTVDSHEPRL GPRPRSHNKV LNPPGGKSSI SFY
Tissue Specificity Expressed in liver, kidney, prostate, testis and uterus.
Function Nicotinic acid adenine dinucleotide phosphate (NAADP) binding protein required for NAADP-evoked intracellular calcium release. Confers NAADP-sensitivity to the two pore channels (TPCs) complex. Enables NAADP to activate Ca(2+) release from the endoplasmic reticulum through ryanodine receptors. (Microbial infection) Involved in the endolysosomal trafficking of human coronavirus SARS-CoV-2.
Protein Name Jupiter Microtubule Associated Homolog 2
Hematological And Neurological Expressed 1-Like Protein
Hn1-Like Protein
Database Links
Cellular Localisation Cytoplasm
Nucleus
Colocalizes With Type 1 Ryanodine Receptor (Ryr1)
Alternative Protein Names Jupiter Microtubule Associated Homolog 2 protein
Hematological And Neurological Expressed 1-Like Protein protein
Hn1-Like Protein protein
JPT2 protein
C16orf34 protein
HN1L protein
L11 protein

Information sourced from Uniprot.org