Human CDK2AP1 protein (Recombinant) (His-Tag) (STJP016621)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human CDK2AP1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.25 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 50% Glycerol, 2mM DTT |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CDK2AP1 |
| Gene ID | 8099 |
| Uniprot ID | CDKA1_HUMAN |
| Accession Number | NP_004633 |
| Immunogen | Human |
| Immunogen Region | 1-115aa |
| Immunogen Sequence | MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMSY KPNLAAHMPA AALNAAGSVH SPSTSMATSS QYRQLLSDYG PPSLGYTQGT GNSQVPQSKY AELLAIIEEL GKEIRPTYAG SKSAMERLKR GIIHARGLVR ECLAETERNA RS |
Additional Info
| Post Translational Modifications | Phosphorylated in vitro by IKBKE at Ser-46. |
| Function | Inhibitor of cyclin-dependent kinase CDK2. Also acts as a component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin. |
| Protein Name | Cyclin-Dependent Kinase 2-Associated Protein 1Cdk2-Associated Protein 1Deleted In Oral Cancer 1Doc-1Putative Oral Cancer Suppressor |
| Database Links | |
| Cellular Localisation | NucleusChromosome |
| Alternative Protein Names | Cyclin-Dependent Kinase 2-Associated Protein 1 proteinCdk2-Associated Protein 1 proteinDeleted In Oral Cancer 1 proteinDoc-1 proteinPutative Oral Cancer Suppressor proteinCDK2AP1 proteinCDKAP1 proteinDOC1 protein |
Information sourced from Uniprot.org