Human HN1L protein (Recombinant) (His-Tag) (STJP018041)

SPECIFICATIONS
HostE.coli
ImmunogenHuman
STJP018041
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General Information

Short DescriptionRecombinant-Human HN1L-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
ApplicationsSDS-PAGE
HostE.coli
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

Concentration1 mg/mL
FormulationLiquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% Glycerol
Storage InstructionFor short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolJPT2
Gene ID90861
Uniprot IDJUPI2_HUMAN
Accession NumberNP_653171.1
ImmunogenHuman
Immunogen Region1-190aa
Immunogen SequenceMFQVPDS EGGRAGSRAM KPPGGESSNL FGSPEEATPS SRPNRMASNI FGPTEEPQNI PKRTNPPGGK GSGIFDESTP VQTRQHLNPP GGKTSDIFGS PVTATSRLAH PNKPKDHVFL CEGEEPKSDL KAARSIPAGA EPGEKGSARK AGPAKEQEPM PTVDSHEPRL GPRPRSHNKV LNPPGGKSSI SFY

Additional Info

Tissue Specificity Expressed in liver, kidney, prostate, testis and uterus.
Function Nicotinic acid adenine dinucleotide phosphate (NAADP) binding protein required for NAADP-evoked intracellular calcium release. Confers NAADP-sensitivity to the two pore channels (TPCs) complex. Enables NAADP to activate Ca(2+) release from the endoplasmic reticulum through ryanodine receptors. (Microbial infection) Involved in the endolysosomal trafficking of human coronavirus SARS-CoV-2.
Protein Name Jupiter Microtubule Associated Homolog 2
Hematological And Neurological Expressed 1-Like Protein
Hn1-Like Protein
Database Links
Cellular Localisation Cytoplasm
Nucleus
Colocalizes With Type 1 Ryanodine Receptor (Ryr1)
Alternative Protein Names Jupiter Microtubule Associated Homolog 2 protein
Hematological And Neurological Expressed 1-Like Protein protein
Hn1-Like Protein protein
JPT2 protein
C16orf34 protein
HN1L protein
L11 protein

Information sourced from Uniprot.org

Citations

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