Human HMGCS1 protein (Recombinant) (His-Tag) (STJP019159)

SPECIFICATIONS
HostE.coli
ImmunogenHuman
STJP019159
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General Information

Short DescriptionRecombinant-Human HMGCS1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
ApplicationsSDS-PAGE
HostE.coli
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

Concentration0.5 mg/mL
FormulationLiquid in phosphate-Buffered Saline (pH 7.4) containing 10% Glycerol, 1mM DTT
Storage InstructionFor short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolHMGCS1
Gene ID3157
Uniprot IDHMCS1_HUMAN
Accession NumberNP_001091742
ImmunogenHuman
Immunogen Region1-520aa
Immunogen SequenceMGSSHHHHHH SSGLVPRGSH MGSMPGSLPL NAEACWPKDV GIVALEIYFP SQYVDQAELE KYDGVDAGKY TIGLGQAKMG FCTDREDINS LCMTVVQNLM ERNNLSYDCI GRLEVGTETI IDKSKSVKTN LMQLFEESGN TDIEGIDTTN ACYGGTAAVF NAVNWIESSS WDGRYALVVA GDIAVYATGN ARPTGGVGAV ALLIGPNAPL IFERGLRGTH MQHAYDFY

Additional Info

Function Catalyzes the condensation of acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is converted by HMG-CoA reductase (HMGCR) into mevalonate, a precursor for cholesterol synthesis.
Protein Name Hydroxymethylglutaryl-Coa Synthase - Cytoplasmic
Hmg-Coa Synthase
3-Hydroxy-3-Methylglutaryl Coenzyme A Synthase
Database Links Reactome: R-HSA-191273
Reactome: R-HSA-1989781
Reactome: R-HSA-2426168
Cellular Localisation Cytoplasm
Alternative Protein Names Hydroxymethylglutaryl-Coa Synthase - Cytoplasmic protein
Hmg-Coa Synthase protein
3-Hydroxy-3-Methylglutaryl Coenzyme A Synthase protein
HMGCS1 protein
HMGCS protein

Information sourced from Uniprot.org

Citations

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