Human HLA-DOA protein (Recombinant) (His-Tag) (STJP018292)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human HLA-DOA-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE/Denatured |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.4M UREA, 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | HLA-DOA |
| Gene ID | 3111 |
| Uniprot ID | DOA_HUMAN |
| Accession Number | NP_002110 |
| Immunogen | Human |
| Immunogen Region | 26-217aa |
| Immunogen Sequence |
Additional Info
| Function | Important modulator in the HLA class II restricted antigen presentation pathway by interaction with the HLA-DM molecule in B-cells. Modifies peptide exchange activity of HLA-DM. |
| Protein Name | Hla Class Ii Histocompatibility Antigen - Do Alpha ChainMhc Dn-AlphaMhc Dz AlphaMhc Class Ii Antigen Doa |
| Database Links | Reactome: R-HSA-2132295 |
| Cellular Localisation | Endosome MembraneSingle-Pass Type I Membrane ProteinLysosome MembraneComplexes With Hla-Dm Molecule During Intracellular Transport And In Endosomal/Lysosomal CompartmentsHeterotetramerization Is Necessary To Exit The Er |
| Alternative Protein Names | Hla Class Ii Histocompatibility Antigen - Do Alpha Chain proteinMhc Dn-Alpha proteinMhc Dz Alpha proteinMhc Class Ii Antigen Doa proteinHLA-DOA proteinHLA-DNA proteinHLA-DZA protein |
Information sourced from Uniprot.org