Human HIP1R protein (Recombinant) (N-His) (STJP003342)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human HIP1R-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | HIP1R |
| Gene ID | 9026 |
| Uniprot ID | HIP1R_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Ser771-Ala1012 |
Additional Info
| Function | Component of clathrin-coated pits and vesicles, that may link the endocytic machinery to the actin cytoskeleton. Binds 3-phosphoinositides (via ENTH domain). May act through the ENTH domain to promote cell survival by stabilizing receptor tyrosine kinases following ligand-induced endocytosis. |
| Protein Name | Huntingtin-Interacting Protein 1-Related ProteinHip1-Related ProteinHuntingtin-Interacting Protein 12Hip-12 |
| Database Links | Reactome: R-HSA-432722Reactome: R-HSA-8856828 |
| Cellular Localisation | CytoplasmPerinuclear RegionEndomembrane SystemCytoplasmic VesicleClathrin-Coated Vesicle MembraneMembrane-Associated ProteinMainly Localized At The Endocytic Compartments And In The Perinuclear Region |
| Alternative Protein Names | Huntingtin-Interacting Protein 1-Related Protein proteinHip1-Related Protein proteinHuntingtin-Interacting Protein 12 proteinHip-12 proteinHIP1R proteinHIP12 proteinKIAA0655 protein |
Information sourced from Uniprot.org