Human HINT2 protein (Recombinant) (His-Tag) (STJP018193)

SPECIFICATIONS
HostE.coli
ImmunogenHuman
STJP018193
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General Information

Short DescriptionRecombinant-Human HINT2-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
ApplicationsSDS-PAGE
HostE.coli
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

Concentration0.5 mg/mL
FormulationLiquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% Glycerol, 1mM DTT
Storage InstructionFor short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolHINT2
Gene ID84681
Uniprot IDHINT2_HUMAN
Accession NumberNP_115982
ImmunogenHuman
Immunogen Region18-163aa
Immunogen SequenceMGSSHHHHHH SSGLVPRGSH MGSVAATGVR GGQVRGAAGV TDGNEVAKAQ QATPGGAAPT IFSRILDKSL PADILYEDQQ CLVFRDVAPQ APVHFLVIPK KPIPRISQAE EEDQQLLGHL LLVAKQTAKA EGLGDGYRLV INDGKLGAQS VYHLHIHVLG GRQLQWPPG

Additional Info

Tissue Specificity High expression in liver and pancreas. Expression is significantly down-regulated in hepatocellular carcinoma (HCC) patients.
Function Exhibits adenosine 5'-monophosphoramidase activity, hydrolyzing purine nucleotide phosphoramidates with a single phosphate group such as adenosine 5'monophosphoramidate (AMP-NH2) to yield AMP and NH2. Hydrolyzes adenosine 5'-O-p-nitrophenylphosphoramidate (AMP-pNA). Hydrolyzes fluorogenic purine nucleoside tryptamine phosphoramidates in vitro. May be involved in steroid biosynthesis. May play a role in apoptosis.
Protein Name Adenosine 5'-Monophosphoramidase Hint2
Hint-3
Hit-17kda
Histidine Triad Nucleotide-Binding Protein 2 - Mitochondrial
Hint-2
Pkci-1-Related Hit Protein
Database Links Reactome: R-HSA-9013405
Cellular Localisation Mitochondrion
Alternative Protein Names Adenosine 5'-Monophosphoramidase Hint2 protein
Hint-3 protein
Hit-17kda protein
Histidine Triad Nucleotide-Binding Protein 2 - Mitochondrial protein
Hint-2 protein
Pkci-1-Related Hit Protein protein
HINT2 protein

Information sourced from Uniprot.org

Citations

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