Human HINT2 protein (Recombinant) (His-Tag) (STJP018193)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human HINT2-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.5 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% Glycerol, 1mM DTT |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | HINT2 |
| Gene ID | 84681 |
| Uniprot ID | HINT2_HUMAN |
| Accession Number | NP_115982 |
| Immunogen | Human |
| Immunogen Region | 18-163aa |
| Immunogen Sequence | MGSSHHHHHH SSGLVPRGSH MGSVAATGVR GGQVRGAAGV TDGNEVAKAQ QATPGGAAPT IFSRILDKSL PADILYEDQQ CLVFRDVAPQ APVHFLVIPK KPIPRISQAE EEDQQLLGHL LLVAKQTAKA EGLGDGYRLV INDGKLGAQS VYHLHIHVLG GRQLQWPPG |
Additional Info
| Tissue Specificity | High expression in liver and pancreas. Expression is significantly down-regulated in hepatocellular carcinoma (HCC) patients. |
| Function | Exhibits adenosine 5'-monophosphoramidase activity, hydrolyzing purine nucleotide phosphoramidates with a single phosphate group such as adenosine 5'monophosphoramidate (AMP-NH2) to yield AMP and NH2. Hydrolyzes adenosine 5'-O-p-nitrophenylphosphoramidate (AMP-pNA). Hydrolyzes fluorogenic purine nucleoside tryptamine phosphoramidates in vitro. May be involved in steroid biosynthesis. May play a role in apoptosis. |
| Protein Name | Adenosine 5'-Monophosphoramidase Hint2Hint-3Hit-17kdaHistidine Triad Nucleotide-Binding Protein 2 - MitochondrialHint-2Pkci-1-Related Hit Protein |
| Database Links | Reactome: R-HSA-9013405 |
| Cellular Localisation | Mitochondrion |
| Alternative Protein Names | Adenosine 5'-Monophosphoramidase Hint2 proteinHint-3 proteinHit-17kda proteinHistidine Triad Nucleotide-Binding Protein 2 - Mitochondrial proteinHint-2 proteinPkci-1-Related Hit Protein proteinHINT2 protein |
Information sourced from Uniprot.org