Human HFE protein (Recombinant) (N-His) (STJP014658)
SPECIFICATIONS
HostE.coli
ConjugationUnconjugated
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human HFE-N-His protein was developed from e.coli and has a target region of N-His. For use in research applications. |
| Applications | ELISA/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Dilution Range | Reconstitute in sterile water for a stock solution. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% SKL, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | Please contact us for this information. |
Target Information
| Gene Symbol | HFE |
| Gene ID | 3077 |
| Uniprot ID | HFE_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Arg23-Val306 |
Additional Info
| Function | Binds to transferrin receptor (TFR) and reduces its affinity for iron-loaded transferrin. |
| Protein Name | Hereditary Hemochromatosis ProteinHla-H |
| Database Links | Reactome: R-HSA-917977 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Hereditary Hemochromatosis Protein proteinHla-H proteinHFE proteinHLAH protein |
Information sourced from Uniprot.org