Human HES7 protein (Recombinant) (His-Tag) (STJP017945)

SPECIFICATIONS
HostE.coli
ImmunogenHuman
STJP017945
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General Information

Short DescriptionRecombinant-Human HES7-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
ApplicationsSDS-PAGE/Denatured
HostE.coli
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

Concentration1 mg/mL
FormulationLiquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% Glycerol
Storage InstructionFor short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolHES7
Gene ID84667
Uniprot IDHES7_HUMAN
Accession NumberNP_001159439
ImmunogenHuman
Immunogen Region1-230aa
Immunogen SequenceMVTRDRA ENRDGPKMLK PLVEKRRRDR INRSLEELRL LLLERTRDQN LRNPKLEKAE ILEFAVGYLR ERSRVEPPAA AAPGVPRSPV QDAEALASCY LSGFRECLLR LAAFAHDASP AARAQLFSAL HGYLRPKPPR PKPVDPRPPA PRPSLDPAAP ALGPALHQRP PVHQGHPSPR CAWSPSLCSP RAGDSGAPAP LTGLLP

Additional Info

Function Transcriptional repressor. Represses transcription from both N box- and E box-containing promoters. May with HES1, cooperatively regulate somite formation in the presomitic mesoderm (PSM). May function as a segmentation clock, which is essential for coordinated somite segmentation.
Protein Name Transcription Factor Hes-7
Hhes7
Class B Basic Helix-Loop-Helix Protein 37
Bhlhb37
Hairy And Enhancer Of Split 7
Bhlh Factor Hes7
Database Links Reactome: R-HSA-9824272
Cellular Localisation Nucleus
Alternative Protein Names Transcription Factor Hes-7 protein
Hhes7 protein
Class B Basic Helix-Loop-Helix Protein 37 protein
Bhlhb37 protein
Hairy And Enhancer Of Split 7 protein
Bhlh Factor Hes7 protein
HES7 protein
BHLHB37 protein

Information sourced from Uniprot.org

Citations

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