Human Hemopexin protein (Recombinant) (His-Tag) (STJP018660)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human Hemopexin-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE/Denatured |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | HPX |
| Gene ID | 3263 |
| Uniprot ID | HEMO_HUMAN |
| Accession Number | NP_000604 |
| Immunogen | Human |
| Immunogen Region | 24-462aa |
| Immunogen Sequence | MGSSHHHHHH SSGLVPRGSH MGSTPLPPTS AHGNVAEGET KPDPDVTERC SDGWSFDATT LDDNGTMLFF KGEFVWKSHK WDRELISERW KNFPSPVDAA FRQGHNSVFL IKGDKVWVYP PEKKEKGYPK LLQDEFPGIP SPLDAAVECH RGECQAEGVL FFQGDREWFW DLATGTMKER SWPAVGNCSS ALRWLGRYYC FQGNQFLRFD PVRGEVPPRY PRDVRDYF |
Additional Info
| Tissue Specificity | Expressed by the liver and secreted in plasma. |
| Post Translational Modifications | N- and O-glycosylated. O-glycosylated with core 1 or possibly core 8 glycans. O-glycosylation in the 30-40 region is minor compared to glycosylation at Thr-24 and Thr-29. |
| Function | Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation. |
| Protein Name | HemopexinBeta-1b-Glycoprotein |
| Database Links | Reactome: R-HSA-2168880 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Hemopexin proteinBeta-1b-GlycoproteinHPX protein |
Information sourced from Uniprot.org