Human HELLS protein (Recombinant) (N-His) (STJP008267)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human HELLS-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | HELLS |
| Gene ID | 3070 |
| Uniprot ID | HELLS_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Asp523-His748 |
Additional Info
| Function | Plays an essential role in normal development and survival. Involved in regulation of the expansion or survival of lymphoid cells. Required for de novo or maintenance DNA methylation. May control silencing of the imprinted CDKN1C gene through DNA methylation. May play a role in formation and organization of heterochromatin, implying a functional role in the regulation of transcription and mitosis. |
| Protein Name | Lymphoid-Specific HelicaseProliferation-Associated Snf2-Like ProteinSwi/Snf2-Related Matrix-Associated Actin-Dependent Regulator Of Chromatin Subfamily A Member 6 |
| Database Links | Reactome: R-HSA-9839394 |
| Cellular Localisation | NucleusClosely Associated With Pericentric Heterochromatin |
| Alternative Protein Names | Lymphoid-Specific Helicase proteinProliferation-Associated Snf2-Like Protein proteinSwi/Snf2-Related Matrix-Associated Actin-Dependent Regulator Of Chromatin Subfamily A Member 6 proteinHELLS proteinPASG proteinSMARCA6 proteinNbla10143 protein |
Information sourced from Uniprot.org