Human HARS protein (Recombinant) (His-Tag) (STJP016866)

SPECIFICATIONS
HostE.coli
ImmunogenHuman
STJP016866
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General Information

Short DescriptionRecombinant-Human HARS-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
ApplicationsSDS-PAGE
HostE.coli
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

Concentration1 mg/mL
FormulationLiquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol, 1mM DTT, 0.1M NaCl.
Storage InstructionFor short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolHARS1
Gene ID3035
Uniprot IDHARS1_HUMAN
Accession NumberNP_002100
ImmunogenHuman
Immunogen Region1-509aa
Immunogen SequenceMAERAAL EELVKLQGER VRGLKQQKAS AELIEEEVAK LLKLKAQLGP DESKQKFVLK TPKGTRDYSP RQMAVREKVF DVIIRCFKRH GAEVIDTPVF ELKETLMGKY GEDSKLIYDL KDQGGELLSL RYDLTVPFAR YLAMNKLTNI KRYHIAKVYR RDNPAMTRGR YREFYQCDFD IAGNFDPMIP DAECLKIMCE ILSSLQ

Additional Info

Tissue Specificity Brain, heart, liver and kidney.
Function Catalyzes the ATP-dependent ligation of histidine to the 3'-end of its cognate tRNA, via the formation of an aminoacyl-adenylate intermediate (His-AMP). Plays a role in axon guidance.
Protein Name Histidine--Trna Ligase - Cytoplasmic
Histidyl-Trna Synthetase
Hisrs
Database Links Reactome: R-HSA-379716
Cellular Localisation Cytoplasm
Alternative Protein Names Histidine--Trna Ligase - Cytoplasmic protein
Histidyl-Trna Synthetase protein
Hisrs protein
HARS1 protein
HARS protein
HRS protein

Information sourced from Uniprot.org

Citations

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