Human HAND2 protein (Recombinant) (N-His-KSI) (STJP015419)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human HAND2-N-His-KSI protein was developed from e.coli for the region N-His-KSI. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | Please contact us for further information. |
Target Information
| Gene Symbol | HAND2 |
| Gene ID | 9464 |
| Uniprot ID | HAND2_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Ser2-Gln217 |
Additional Info
| Function | Essential for cardiac morphogenesis, particularly for the formation of the right ventricle and of the aortic arch arteries. Required for vascular development and regulation of angiogenesis, possibly through a VEGF signaling pathway. Also plays an important role in limb development, particularly in the establishment of anterior-posterior polarization, acting as an upstream regulator of sonic hedgehog (SHH) induction in the limb bud. Is involved in the development of branchial arches, which give rise to unique structures in the head and neck. Binds DNA on E-box consensus sequence 5'-CANNTG-3'. |
| Protein Name | Heart- And Neural Crest Derivatives-Expressed Protein 2Class A Basic Helix-Loop-Helix Protein 26Bhlha26Deciduum - Heart - Autonomic Nervous System And Neural Crest Derivatives-Expressed Protein 2Dhand |
| Database Links | Reactome: R-HSA-8878166Reactome: R-HSA-9733709 |
| Cellular Localisation | Nucleus |
| Alternative Protein Names | Heart- And Neural Crest Derivatives-Expressed Protein 2 proteinClass A Basic Helix-Loop-Helix Protein 26 proteinBhlha26 proteinDeciduum - Heart - Autonomic Nervous System And Neural Crest Derivatives-Expressed Protein 2 proteinDhand proteinHAND2 proteinBHLHA26 proteinDHAND protein |
Information sourced from Uniprot.org