| Short Description : | Recombinant-Human HAI-2A-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications: | SDS-PAGE/Denatured |
| Host: | E.coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Concentration: | 0.5 mg/mL |
| Formulation: | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea 10% Glycerol |
| Storage Instruction: | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SPINT2 |
| Gene ID: | 10653 |
| Uniprot ID: | SPIT2_HUMAN |
| Accession Number: | NP_066925 |
| Immunogen: | Human |
| Immunogen Region: | 28-197aa |
| Immunogen Sequence: | MGSSHHHHHH SSGLVPRGSH MGSHMADRER SIHDFCLVSK VVGRCRASMP RWWYNVTDGS CQLFVYGGCD GNSNNYLTKE ECLKKCATVT ENATGDLATS RNAADSSVPS APRRQDSEDH SSDMFNYEEY CTANAVTGPC RASFPRWYFD VERNSCNNFI YGGCRGNKNS YRSEEACMLR CFRQQENPPL PLGSK |
| Tissue Specificity | Expressed in placenta, kidney, pancreas, prostate, testis, thymus, and trachea. |
| Function | Inhibitor of HGFAC. Also inhibits plasmin, and plasma and tissue kallikrein. Inhibits serine protease activity of TMPRSS13. Inhibits serine protease activity of ST14/matriptase and PRSS8/prostasin in vitro. |
| Protein Name | Kunitz-Type Protease Inhibitor 2Hepatocyte Growth Factor Activator Inhibitor Type 2Hai-2Placental Bikunin |
| Database Links | Reactome: R-HSA-6806942Reactome: R-HSA-8852405 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinCytoplasm |
| Alternative Protein Names | Kunitz-Type Protease Inhibitor 2 proteinHepatocyte Growth Factor Activator Inhibitor Type 2 proteinHai-2 proteinPlacental Bikunin proteinSPINT2 proteinHAI2 proteinKOP protein |
Information sourced from Uniprot.org
