Name: Human HADH protein (Recombinant) (His-Tag) (STJP016642)
SKU: STJP016642
Availability: InStock

Human HADH protein (Recombinant) (His-Tag) (STJP016642)

SKU:

STJP016642

£125.50 - £649.50

Short Description :	Recombinant-Human HADH-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications:	SDS-PAGE
Host:	E.coli
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Concentration:	1 mg/mL
Formulation:	Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 20% Glycerol, 0.1M NaCl
Storage Instruction:	For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.

Gene Symbol:	HADH
Gene ID:	3033
Uniprot ID:	HCDH_HUMAN
Accession Number:	AAH00306
Immunogen:	Human
Immunogen Region:	13-314aa
Immunogen Sequence:	MSSSSTASAS AKKIIVKHVT VIGGGLMGAG IAQVAAATGH TVVLVDQTED ILAKSKKGIE ESLRKVAKKK FAENPKAGDE FVEKTLSTIA TSTDAASVVH STDLVVEAIV ENLKVKNELF KRLDKFAAEH TIFASNTSSL QITSIANATT RQDRFAGLHF FNPVPVMKLV EVIKTPMTSQ KTFESLVDFS KALGKHPVSC KDTPGF

Tissue Specificity	Expressed in liver, kidney, pancreas, heart and skeletal muscle.
Post Translational Modifications	Succinylation at Lys-81, adjacent to a coenzyme A binding site. Desuccinylated by SIRT5.
Function	Mitochondrial fatty acid beta-oxidation enzyme that catalyzes the third step of the beta-oxidation cycle for medium and short-chain 3-hydroxy fatty acyl-CoAs (C4 to C10). Plays a role in the control of insulin secretion by inhibiting the activation of glutamate dehydrogenase 1 (GLUD1), an enzyme that has an important role in regulating amino acid-induced insulin secretion. Plays a role in the maintenance of normal spermatogenesis through the reduction of fatty acid accumulation in the testes.
Protein Name	Hydroxyacyl-Coenzyme A Dehydrogenase - Mitochondrial Hcdh Medium And Short-Chain L-3-Hydroxyacyl-Coenzyme A Dehydrogenase Short-Chain 3-Hydroxyacyl-Coa Dehydrogenase
Database Links	Reactome: R-HSA-77310 Reactome: R-HSA-77346 Reactome: R-HSA-77348 Reactome: R-HSA-77350 Reactome: R-HSA-77352 Reactome: R-HSA-9837999
Cellular Localisation	Mitochondrion Matrix
Alternative Protein Names	Hydroxyacyl-Coenzyme A Dehydrogenase - Mitochondrial protein Hcdh protein Medium And Short-Chain L-3-Hydroxyacyl-Coenzyme A Dehydrogenase protein Short-Chain 3-Hydroxyacyl-Coa Dehydrogenase protein HADH protein HAD protein HAD1 protein HADHSC protein SCHAD protein

Information sourced from Uniprot.org

Model	Name	Host	Application
STJP005525	Human HADH protein (Recombinant) (N-His) (STJP005525)	E.coli	ELISA/Immunogen/SDS-PAGE/WB
STJP019170	Human FGB protein (Recombinant) (His-Tag) (STJP019170)	E.coli	SDS-PAGE
STJP019149	Human PYCR2 protein (Recombinant) (His-Tag) (STJP019149)	E.coli	SDS-PAGE
STJP019163	Human ALDH6A1 protein (Recombinant) (His-Tag) (STJP019163)	E.coli	SDS-PAGE
STJP019189	Human UBE2Q2 protein (Recombinant) (His-Tag) (STJP019189)	E.coli	SDS-PAGE

Human HADH protein (Recombinant) (His-Tag) (STJP016642)

General Information