Human GULP1/CED-6 protein (Recombinant) (His-Tag) (STJP018116)

SPECIFICATIONS
HostE.coli
ImmunogenHuman
STJP018116
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General Information

Short DescriptionRecombinant-Human GULP1/CED-6-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
ApplicationsSDS-PAGE
HostE.coli
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

Concentration0.5 mg/mL
FormulationLiquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 50% Glycerol, 2mM DTT
Storage InstructionFor short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolGULP1
Gene ID51454
Uniprot IDGULP1_HUMAN
Accession NumberNP_057399
ImmunogenHuman
Immunogen Region1-304aa
Immunogen SequenceMNRAFSR KKDKTWMHTP EALSKHFIPY NAKFLGSTEV EQPKGTEVVR DAVRKLKFAR HIKKSEGQKI PKVELQISIY GVKILEPKTK EVQHNCQLHR ISFCADDKTD KRIFTFICKD SESNKHLCYV FDSEKCAEEI TLTIGQAFDL AYRKFLESGG KDVETRKQIA GLQKRIQDLE TENMELKNKV QDLENQLRIT QVSAPP

Additional Info

Tissue Specificity Widely expressed. Detected in macrophages, pancreas, kidney, skeletal muscle, heart, colon, intestine, lung, placenta and ovary.
Function May function as an adapter protein. Required for efficient phagocytosis of apoptotic cells. Modulates cellular glycosphingolipid and cholesterol transport. May play a role in the internalization and endosomal trafficking of various LRP1 ligands, such as PSAP. Increases cellular levels of GTP-bound ARF6.
Protein Name Ptb Domain-Containing Engulfment Adapter Protein 1
Cell Death Protein 6 Homolog
Ptb Domain Adapter Protein Ced-6
Protein Gulp
Database Links
Cellular Localisation Cytoplasm
May Associate With The Cytoplasmic Side Of The Plasma Membrane And Early Endosomes
Alternative Protein Names Ptb Domain-Containing Engulfment Adapter Protein 1 protein
Cell Death Protein 6 Homolog protein
Ptb Domain Adapter Protein Ced-6 protein
Protein Gulp protein
GULP1 protein
CED6 protein
GULP protein

Information sourced from Uniprot.org

Citations

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