| Host: | E. coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human GUCY1A2-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Gene Symbol: | GUCY1A2 |
| Gene ID: | 2977 |
| Uniprot ID: | GCYA2_HUMAN |
| Immunogen Region: | Ser496-Arg700 |
| Immunogen: | Homo sapiens (Human) |
| Function | Has guanylyl cyclase on binding to the beta-1 subunit. Isoform 2 acts as a negative regulator of guanylyl cyclase activity as it forms non-functional heterodimers with the beta subunits. |
| Protein Name | Guanylate Cyclase Soluble Subunit Alpha-2Gcs-Alpha-2 |
| Database Links | Reactome: R-HSA-392154Reactome: R-HSA-445355 |
| Cellular Localisation | Cytoplasm |
| Alternative Protein Names | Guanylate Cyclase Soluble Subunit Alpha-2 proteinGcs-Alpha-2 proteinGUCY1A2 proteinGUC1A2 proteinGUCSA2 protein |
Information sourced from Uniprot.org