Human GTF2A1 protein (Recombinant) (His-Tag) (STJP018571)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human GTF2A1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.5 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 20% Glycerol, 0.15M NaCl, 1mM DTT |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | GTF2A1 |
| Gene ID | 2957 |
| Uniprot ID | TF2AA_HUMAN |
| Accession Number | NP_056943 |
| Immunogen | Human |
| Immunogen Region | 1-274aa |
| Immunogen Sequence |
Additional Info
| Post Translational Modifications | The alpha and beta subunits are postranslationally produced from the precursor form by TASP1. The cleavage promotes proteasomal degradation. |
| Function | TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with TBP mediates transcriptional activity. |
| Protein Name | Transcription Initiation Factor Iia Subunit 1General Transcription Factor Iia Subunit 1TfiialTranscription Initiation Factor Tfiia 42 Kda SubunitTfiia-42 Cleaved Into - Transcription Initiation Factor Iia Alpha ChainTfiia P35 Subunit - Transcription Initiation Factor Iia Beta ChainTfiia P19 Subunit |
| Database Links | Reactome: R-HSA-167161Reactome: R-HSA-167162Reactome: R-HSA-167172Reactome: R-HSA-674695Reactome: R-HSA-6807505Reactome: R-HSA-73776Reactome: R-HSA-73779Reactome: R-HSA-75953Reactome: R-HSA-76042Reactome: R-HSA-9018519 |
| Cellular Localisation | Nucleus |
| Alternative Protein Names | Transcription Initiation Factor Iia Subunit 1 proteinGeneral Transcription Factor Iia Subunit 1 proteinTfiial proteinTranscription Initiation Factor Tfiia 42 Kda Subunit proteinTfiia-42 Cleaved Into - Transcription Initiation Factor Iia Alpha Chain proteinTfiia P35 Subunit - Transcription Initiation Factor Iia Beta Chain proteinTfiia P19 Subunit proteinGTF2A1 proteinTF2A1 protein |
Information sourced from Uniprot.org