| Short Description : | Recombinant-Human GRPEL1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications: | SDS-PAGE |
| Host: | E.coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Concentration: | 1 mg/mL |
| Formulation: | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 1mM DTT, 10% Glycerol |
| Storage Instruction: | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | GRPEL1 |
| Gene ID: | 80273 |
| Uniprot ID: | GRPE1_HUMAN |
| Accession Number: | NP_079472 |
| Immunogen: | Human |
| Immunogen Region: | 28-217aa |
| Immunogen Sequence: | MGSSHHHHHH SSGLVPRGSH MCTATKQKNS GQNLEEDMGQ SEQKADPPAT EKTLLEEKVK LEEQLKETVE KYKRALADTE NLRQRSQKLV EEAKLYGIQA FCKDLLEVAD VLEKATQCVP KEEIKDDNPH LKNLYEGLVM TEVQIQKVFT KHGLLKLNPV GAKFDPYEHE ALFHTPVEGK EPGTVALVSK VGYKLHGRTL RPALVGVVKE A |
| Function | Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins. |
| Protein Name | Grpe Protein Homolog 1 - MitochondrialHmgeMt-Grpe#1 |
| Database Links | Reactome: R-HSA-1268020 |
| Cellular Localisation | Mitochondrion Matrix |
| Alternative Protein Names | Grpe Protein Homolog 1 - Mitochondrial proteinHmge proteinMt-Grpe#1 proteinGRPEL1 proteinGREPEL1 protein |
Information sourced from Uniprot.org
