Human GRO gamma/CXCL3 protein (Recombinant) (His-Tag) (STJP019602)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human GRO gamma/CXCL3-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.5 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 20% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Endotoxin | < 1 EU per 1ug of protein (determined by LAL method) |
Target Information
| Gene Symbol | CXCL3 |
| Gene ID | 2921 |
| Uniprot ID | CXCL3_HUMAN |
| Accession Number | NP_002081 |
| Immunogen | Human |
| Immunogen Region | 35-107aa |
| Immunogen Sequence | MGSSHHHHHH SSGLVPRGSH MASVVTELRC QCLQTLQGIH LKNIQSVNVR SPGPHCAQTE VIATLKNGKK ACLNPASPMV QKIIEKILNK GSTN |
Additional Info
| Post Translational Modifications | N-terminal processed form GRO-gamma(5-73) is produced by proteolytic cleavage after secretion from peripheral blood monocytes. |
| Function | Ligand for CXCR2. Has chemotactic activity for neutrophils. May play a role in inflammation and exert its effects on endothelial cells in an autocrine fashion. In vitro, the processed form GRO-gamma(5-73) shows a fivefold higher chemotactic activity for neutrophilic granulocytes. |
| Protein Name | C-X-C Motif Chemokine 3Gro-Gamma(1-73Growth-Regulated Protein GammaGro-GammaMacrophage Inflammatory Protein 2-BetaMip2-Beta Cleaved Into - Gro-Gamma(5-73 |
| Database Links | Reactome: R-HSA-380108Reactome: R-HSA-418594 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | C-X-C Motif Chemokine 3 proteinGro-Gamma(1-73 proteinGrowth-Regulated Protein Gamma proteinGro-Gamma proteinMacrophage Inflammatory Protein 2-Beta proteinMip2-Beta Cleaved Into - Gro-Gamma(5-73 proteinCXCL3 proteinGRO3 proteinGROG proteinSCYB3 protein |
Information sourced from Uniprot.org