Human GRO beta/CXCL2 protein (Recombinant) (His-Tag) (STJP016446)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human GRO beta/CXCL2-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Endotoxin | < 1 EU per 1ug of protein (determined by LAL method) |
Target Information
| Gene Symbol | CXCL2 |
| Gene ID | 2920 |
| Uniprot ID | CXCL2_HUMAN |
| Accession Number | NP_002080 |
| Immunogen | Human |
| Immunogen Region | 35-107aa |
| Immunogen Sequence |
Additional Info
| Post Translational Modifications | The N-terminal processed form GRO-beta(5-73) is produced by proteolytic cleavage after secretion from bone marrow stromal cells. |
| Function | Produced by activated monocytes and neutrophils and expressed at sites of inflammation. Hematoregulatory chemokine, which, in vitro, suppresses hematopoietic progenitor cell proliferation. GRO-beta(5-73) shows a highly enhanced hematopoietic activity. |
| Protein Name | C-X-C Motif Chemokine 2Growth-Regulated Protein BetaGro-BetaMacrophage Inflammatory Protein 2-AlphaMip2-Alpha Cleaved Into - Gro-Beta(5-73Gro-Beta-THematopoietic Synergistic FactorHsfSb-251353 |
| Database Links | Reactome: R-HSA-380108Reactome: R-HSA-418594Reactome: R-HSA-6783783 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | C-X-C Motif Chemokine 2 proteinGrowth-Regulated Protein Beta proteinGro-Beta proteinMacrophage Inflammatory Protein 2-Alpha proteinMip2-Alpha Cleaved Into - Gro-Beta(5-73 proteinGro-Beta-T proteinHematopoietic Synergistic Factor proteinHsf proteinSb-251353 proteinCXCL2 proteinGRO2 proteinGROB proteinMIP2A proteinSCYB2 protein |
Information sourced from Uniprot.org