Human GRO alpha (GRO alpha) Antibody Pair (STJAP00706)
General Information
| Short Description | This GRO alpha antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the. |
| Applications | ELISA |
| Host | Rabbit/Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal/Monoclonal |
| Clone ID | R05-8F6/R08-8D0 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | Determined by end user |
| Formulation | 0.01M PBS, pH 7.2 |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | CXCL1 |
| Gene ID | 2919 |
| Uniprot ID | GROA_HUMAN |
| Immunogen | Recombinant protein of human GRO alpha |
Additional Info
| Post Translational Modifications | N-terminal processed forms GRO-alpha(4-73), GRO-alpha(5-73) and GRO-alpha(6-73) are produced by proteolytic cleavage after secretion from peripheral blood monocytes. |
| Function | Has chemotactic activity for neutrophils. May play a role in inflammation and exerts its effects on endothelial cells in an autocrine fashion. In vitro, the processed forms GRO-alpha(4-73), GRO-alpha(5-73) and GRO-alpha(6-73) show a 30-fold higher chemotactic activity. |
| Protein Name | Growth-Regulated Alpha ProteinC-X-C Motif Chemokine 1Gro-Alpha(1-73Melanoma Growth Stimulatory ActivityMgsaNeutrophil-Activating Protein 3Nap-3 Cleaved Into - Gro-Alpha(4-73 - Gro-Alpha(5-73 - Gro-Alpha(6-73 |
| Database Links | Reactome: R-HSA-380108Reactome: R-HSA-418594Reactome: R-HSA-6783783Reactome: R-HSA-6798695 |
| Cellular Localisation | Secreted |
| Alternative Antibody Pair Names | Growth-Regulated Alpha Protein antibody pairC-X-C Motif Chemokine 1 antibody pairGro-Alpha(1-73 antibody pairMelanoma Growth Stimulatory Activity antibody pairMgsa antibody pairNeutrophil-Activating Protein 3 antibody pairNap-3 Cleaved Into - Gro-Alpha(4-73 - Gro-Alpha(5-73 - Gro-Alpha(6-73 antibody pairCXCL1 antibody pairGRO antibody pairGRO1 antibody pairGROA antibody pairMGSA antibody pairSCYB1 antibody pair |
Information sourced from Uniprot.org
Citations
Product Review
Frequently Asked Questions
Common questions about Human GRO alpha (GRO alpha) Antibody Pair (STJAP00706)
This antibody pair detects human GRO alpha (UniProt P09341) and is validated for human reactivity only. Both antibodies were raised against a recombinant protein of human GRO alpha.
Both antibodies are supplied as unconjugated, affinity-purified rabbit monoclonal IgGs at 1 mg/mL, formulated in 0.01M PBS at pH 7.2. The clone IDs are R05-8F6 and R08-8D0.
This antibody pair is validated for use in ELISA. The appropriate working dilution for each component should be determined by the end user.
Both antibodies are supplied unconjugated, so the user is responsible for any labeling or conjugation steps required for their specific assay setup. This is standard practice when configuring a sandwich ELISA with a separate capture and detection antibody.
Both components should be stored at 4°C for short-term use. For long-term storage, aliquot and store at -20°C. Repeated freeze/thaw cycles should be avoided to maintain activity.
Orders typically arrive within 1 to 2 weeks, and often sooner depending on your location. If your timeline is critical, please contact us before ordering and we can advise on current lead times.
This product is shipped on gel ice packs to maintain integrity during transit. Priority shipping is used as standard to minimise time in transit.
A Certificate of Analysis (CoA) is provided with every order. If you do not receive one, please contact us and we will issue it promptly.