Human GRO alpha/CXCL1 protein (Recombinant) (His-Tag) (STJP019601)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human GRO alpha/CXCL1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Endotoxin | < 1 EU per 1ug of protein (determined by LAL method) |
Target Information
| Gene Symbol | CXCL1 |
| Gene ID | 2919 |
| Uniprot ID | GROA_HUMAN |
| Accession Number | NP_001502 |
| Immunogen | Human |
| Immunogen Region | 35-107aa |
| Immunogen Sequence |
Additional Info
| Post Translational Modifications | N-terminal processed forms GRO-alpha(4-73), GRO-alpha(5-73) and GRO-alpha(6-73) are produced by proteolytic cleavage after secretion from peripheral blood monocytes. |
| Function | Has chemotactic activity for neutrophils. May play a role in inflammation and exerts its effects on endothelial cells in an autocrine fashion. In vitro, the processed forms GRO-alpha(4-73), GRO-alpha(5-73) and GRO-alpha(6-73) show a 30-fold higher chemotactic activity. |
| Protein Name | Growth-Regulated Alpha ProteinC-X-C Motif Chemokine 1Gro-Alpha(1-73Melanoma Growth Stimulatory ActivityMgsaNeutrophil-Activating Protein 3Nap-3 Cleaved Into - Gro-Alpha(4-73 - Gro-Alpha(5-73 - Gro-Alpha(6-73 |
| Database Links | Reactome: R-HSA-380108Reactome: R-HSA-418594Reactome: R-HSA-6783783Reactome: R-HSA-6798695 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Growth-Regulated Alpha Protein proteinC-X-C Motif Chemokine 1 proteinGro-Alpha(1-73 proteinMelanoma Growth Stimulatory Activity proteinMgsa proteinNeutrophil-Activating Protein 3 proteinNap-3 Cleaved Into - Gro-Alpha(4-73 - Gro-Alpha(5-73 - Gro-Alpha(6-73 proteinCXCL1 proteinGRO proteinGRO1 proteinGROA proteinMGSA proteinSCYB1 protein |
Information sourced from Uniprot.org