Human GPR177/WLS protein (Recombinant) (His-Tag) (STJP018122)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human GPR177/WLS-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE/Denatured |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | WLS |
| Gene ID | 79971 |
| Uniprot ID | WLS_HUMAN |
| Accession Number | NP_079187 |
| Immunogen | Human |
| Immunogen Region | 101-232aa |
| Immunogen Sequence | MGSSHHHHHH SSGLVPRGSH MGSMEMSPWF QFMLFILQLD IAFKLNNQIR ENAEVSMDVS LAYRDDAFAE WTEMAHERVP RKLKCTFTSP KTPEHEGRYY ECDVLPFMEI GSVAHKFYLL NIRLPVNEKK KINVGIGEIK DIRLVGIHQN GGFTK |
Additional Info
| Post Translational Modifications | N-glycosylated. |
| Function | Regulates Wnt proteins sorting and secretion in a feedback regulatory mechanism. This reciprocal interaction plays a key role in the regulation of expression, subcellular location, binding and organelle-specific association of Wnt proteins. Plays also an important role in establishment of the anterior-posterior body axis formation during development. |
| Protein Name | Protein Wntless HomologIntegral Membrane Protein Gpr177Protein Evenness Interrupted HomologEviPutative Nf-Kappa-B-Activating Protein 373 |
| Database Links | Reactome: R-HSA-3238698 |
| Cellular Localisation | Golgi Apparatus MembraneMulti-Pass Membrane ProteinCytoplasmic Vesicle MembraneCell MembraneEndoplasmic Reticulum MembraneEarly Endosome MembraneCo-Localizes With The Adaptin Ap2a2 At Distinct Punctae |
| Alternative Protein Names | Protein Wntless Homolog proteinIntegral Membrane Protein Gpr177 proteinProtein Evenness Interrupted Homolog proteinEvi proteinPutative Nf-Kappa-B-Activating Protein 373 proteinWLS proteinC1orf139 proteinGPR177 proteinUNQ85 proteinPRO18667 protein |
Information sourced from Uniprot.org