Human GPIHBP1 protein (Recombinant) (C-Fc) (STJP013635)
SPECIFICATIONS
HostMammalian Cells
ConjugationUnconjugated
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human GPIHBP1-C-Fc protein was developed from mammalian cells and has a target region of C-Fc. For use in research applications. |
| Applications | ELISA/WB |
| Host | Mammalian Cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Dilution Range | Reconstitute in sterile water for a stock solution. |
| Formulation | Lyophilized from a 0.22 Mu m filtered solution in PBS, pH 7.4. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | < 1 EU/µg as determined by LAL test. |
Target Information
| Gene Symbol | GPIHBP1 |
| Gene ID | 338328 |
| Uniprot ID | HDBP1_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Thr22-Gly151 |
Additional Info
| Function | Mediates the transport of lipoprotein lipase LPL from the basolateral to the apical surface of endothelial cells in capillaries. Anchors LPL on the surface of endothelial cells in the lumen of blood capillaries. Protects LPL against loss of activity, and against ANGPTL4-mediated unfolding. Thereby, plays an important role in lipolytic processing of chylomicrons by LPL, triglyceride metabolism and lipid homeostasis. Binds chylomicrons and phospholipid particles that contain APOA5. Binds high-density lipoprotein (HDL) and plays a role in the uptake of lipids from HDL. |
| Protein Name | Glycosylphosphatidylinositol-Anchored High Density Lipoprotein-Binding Protein 1Gpi-Hbp1Gpi-Anchored Hdl-Binding Protein 1High Density Lipoprotein-Binding Protein 1 |
| Database Links | Reactome: R-HSA-163125Reactome: R-HSA-8963889Reactome: R-HSA-8963901Reactome: R-HSA-975634 |
| Cellular Localisation | Apical Cell MembraneLipid-AnchorGpi-AnchorBasolateral Cell MembraneCell Membrane |
| Alternative Protein Names | Glycosylphosphatidylinositol-Anchored High Density Lipoprotein-Binding Protein 1 proteinGpi-Hbp1 proteinGpi-Anchored Hdl-Binding Protein 1 proteinHigh Density Lipoprotein-Binding Protein 1 proteinGPIHBP1 proteinHBP1 protein |
Information sourced from Uniprot.org