Tissue Specificity | |
Post Translational Modifications | |
Function | Mitochondrial membrane protein that catalyzes the essential first step of biosynthesis of glycerolipids such as triglycerides, phosphatidic acids and lysophosphatidic acids. Esterifies acyl-group from acyl-coenzyme A (acyl-CoA) to the sn-1 position of glycerol-3-phosphate, to produce lysophosphatidic acid. Has a narrow hydrophobic binding cleft that selects for a linear acyl chain. Catalytic activity is higher for substrates with a 16-carbon acyl chain. |
Protein Name | Glycerol-3-Phosphate Acyltransferase 1 - MitochondrialGpat-1 |
Database Links | Reactome: R-HSA-1483166Reactome: R-HSA-2426168Reactome: R-HSA-75109Reactome: R-HSA-8931987Reactome: R-HSA-9018519 |
Cellular Localisation | Mitochondrion Outer MembranePeripheral Membrane ProteinAssociated With The Mitochondrion Outer Membrane Of Hepatic Cells Via A Patch Of Basic Residues |
Alternative ELISA Names | Glycerol-3-Phosphate Acyltransferase 1 - Mitochondrial ELISA kitGpat-1 ELISA kitGPAM ELISA kitGPAT1 ELISA kitKIAA1560 ELISA kit |
output | |
Information sourced from Uniprot.org