Human GOT2 protein (Recombinant) (His-Tag) (STJP019205)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human GOT2-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE/Enzyme Activity |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.5 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol, 1mM DTT, 0.15M NaCl |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Endotoxin | < 1 EU per 1ug of protein (determined by LAL method) |
| Immunoreactivity | Specific activity is > 60unit/mg, and is defined as the amount of enzyme that convert 1umole of alpha-ketoglutarate to L-Glutamate per minute at pH 8.0 at 25C. |
Target Information
| Gene Symbol | GOT2 |
| Gene ID | 2806 |
| Uniprot ID | AATM_HUMAN |
| Accession Number | NP_002071.2 |
| Immunogen | Human |
| Immunogen Region | 30-430aa |
| Immunogen Sequence |
Additional Info
| Function | Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA). As a member of the malate-aspartate shuttle, it has a key role in the intracellular NAD(H) redox balance. Is important for metabolite exchange between mitochondria and cytosol, and for amino acid metabolism. Facilitates cellular uptake of long-chain free fatty acids. |
| Protein Name | Aspartate Aminotransferase - MitochondrialMaspatFatty Acid-Binding ProteinFabp-1Glutamate Oxaloacetate Transaminase 2Kynurenine Aminotransferase 4Kynurenine Aminotransferase IvKynurenine--Oxoglutarate Transaminase 4Kynurenine--Oxoglutarate Transaminase IvPlasma Membrane-Associated Fatty Acid-Binding ProteinFabppmTransaminase A |
| Database Links | Reactome: R-HSA-1614558Reactome: R-HSA-389661Reactome: R-HSA-8963693Reactome: R-HSA-8964539Reactome: R-HSA-9856872 |
| Cellular Localisation | Mitochondrion MatrixCell MembraneExposure To Alcohol Promotes Translocation To The Cell Membrane |
| Alternative Protein Names | Aspartate Aminotransferase - Mitochondrial proteinMaspat proteinFatty Acid-Binding Protein proteinFabp-1 proteinGlutamate Oxaloacetate Transaminase 2 proteinKynurenine Aminotransferase 4 proteinKynurenine Aminotransferase Iv proteinKynurenine--Oxoglutarate Transaminase 4 proteinKynurenine--Oxoglutarate Transaminase Iv proteinPlasma Membrane-Associated Fatty Acid-Binding Protein proteinFabppm proteinTransaminase A proteinGOT2 proteinKYAT4 protein |
Information sourced from Uniprot.org