Human GNB1 protein (Recombinant) (His-Tag) (STJP018761)

SPECIFICATIONS
HostE.coli
ImmunogenHuman
STJP018761
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General Information

Short DescriptionRecombinant-Human GNB1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
ApplicationsSDS-PAGE/Denatured
HostE.coli
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

Concentration0.25 mg/mL
FormulationLiquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.4M UREA, 10% Glycerol
Storage InstructionFor short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolGNB1
Gene ID2782
Uniprot IDGBB1_HUMAN
Accession NumberNP_002065
ImmunogenHuman
Immunogen Region1-340aa
Immunogen SequenceMSELDQL RQEAEQLKNQ IRDARKACAD ATLSQITNNI DPVGRIQMRT RRTLRGHLAK IYAMHWGTDS RLLVSASQDG KLIIWDSYTT NKVHAIPLRS SWVMTCAYAP SGNYVACGGL DNICSIYNLK TREGNVRVSR ELAGHTGYLS CCRFLDDNQI VTSSGDTTCA LWDIETGQQT TTFTGHTGDV MSLSLAPDTR LFVSGA

Additional Info

Post Translational Modifications Phosphorylation at His-266 by NDKB contributes to G protein activation by increasing the high energetic phosphate transfer onto GDP.
Function Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
Protein Name Guanine Nucleotide-Binding Protein G(I/G(S/G(T Subunit Beta-1
Transducin Beta Chain 1
Database Links Reactome: R-HSA-1296041
Reactome: R-HSA-163359
Reactome: R-HSA-202040
Reactome: R-HSA-2485179
Reactome: R-HSA-2514859
Reactome: R-HSA-381676
Reactome: R-HSA-381753
Reactome: R-HSA-381771
Reactome: R-HSA-392170
Reactome: R-HSA-392451
Reactome: R-HSA-392851
Reactome: R-HSA-400042
Reactome: R-HSA-4086398
Reactome: R-HSA-416476
Reactome: R-HSA-416482
Reactome: R-HSA-418217
Reactome: R-HSA-418555
Reactome: R-HSA-418592
Reactome: R-HSA-418594
Reactome: R-HSA-418597
Reactome: R-HSA-420092
Reactome: R-HSA-428930
Reactome: R-HSA-432040
Reactome: R-HSA-456926
Reactome: R-HSA-500657
Reactome: R-HSA-6814122
Reactome: R-HSA-8964315
Reactome: R-HSA-8964616
Reactome: R-HSA-9009391
Reactome: R-HSA-9634597
Reactome: R-HSA-9660821
Reactome: R-HSA-9717207
Reactome: R-HSA-9856530
Reactome: R-HSA-997272
Cellular Localisation
Alternative Protein Names Guanine Nucleotide-Binding Protein G(I/G(S/G(T Subunit Beta-1 protein
Transducin Beta Chain 1 protein
GNB1 protein

Information sourced from Uniprot.org

Citations

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