Human GLYAT protein (Recombinant) (His-Tag) (STJP017254)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human GLYAT-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.5 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 20% Glycerol, 1mM DTT |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | GLYAT |
| Gene ID | 10249 |
| Uniprot ID | GLYAT_HUMAN |
| Accession Number | NP_964011 |
| Immunogen | Human |
| Immunogen Region | 1-296aa |
| Immunogen Sequence |
Additional Info
| Tissue Specificity | Predominantly expressed in liver (at protein level) and kidney. Down-regulated in hepatocellular carcinoma and other liver cancers. |
| Function | Mitochondrial acyltransferase which transfers an acyl group to the N-terminus of glycine and glutamine, although much less efficiently. Can conjugate numerous substrates to form a variety of N-acylglycines, with a preference for benzoyl-CoA over phenylacetyl-CoA as acyl donors. Thereby detoxify xenobiotics, such as benzoic acid or salicylic acid, and endogenous organic acids, such as isovaleric acid. |
| Protein Name | Glycine N-AcyltransferaseAcyl-Coa -Glycine N-AcyltransferaseAacAralkyl Acyl-Coa N-AcyltransferaseAralkyl Acyl-Coa -Amino Acid N-AcyltransferaseBenzoyl-Coenzyme A -Glycine N-AcyltransferaseGlycine N-BenzoyltransferaseHrp-1(Clp |
| Database Links | Reactome: R-HSA-177128Reactome: R-HSA-177135Reactome: R-HSA-9749641 |
| Cellular Localisation | Mitochondrion |
| Alternative Protein Names | Glycine N-Acyltransferase proteinAcyl-Coa -Glycine N-Acyltransferase proteinAac proteinAralkyl Acyl-Coa N-Acyltransferase proteinAralkyl Acyl-Coa -Amino Acid N-Acyltransferase proteinBenzoyl-Coenzyme A -Glycine N-Acyltransferase proteinGlycine N-Benzoyltransferase proteinHrp-1(Clp proteinGLYAT proteinACGNAT proteinCAT proteinGAT protein |
Information sourced from Uniprot.org