Human Glutathione S-Transferase pi 1/GSTP1 protein (Recombinant) (His-Tag) (STJP016484)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human Glutathione S-Transferase pi 1/GSTP1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE/Enzyme Activity |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.5 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 7.0) containing 30% Glycerol, 1mM EDTA, 0.1mM PMSF. |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Endotoxin | < 1 EU per 1ug of protein (determined by LAL method) |
| Immunoreactivity | Specific activity is > 80unit/mg, and is defined as the amount of enzyme that conjugate 1.0 umole of 1-chloro-2, 4-dinitrobenzene (CDNB) with reduced glutathione per minute at pH 6.5 at 25C. |
Target Information
| Gene Symbol | GSTP1 |
| Gene ID | 2950 |
| Uniprot ID | GSTP1_HUMAN |
| Accession Number | NP_000843 |
| Immunogen | Human |
| Immunogen Region | 1-210aa |
| Immunogen Sequence |
Additional Info
| Function | Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2). Participates in the formation of novel hepoxilin regioisomers. Negatively regulates CDK5 activity via p25/p35 translocation to prevent neurodegeneration. |
| Protein Name | Glutathione S-Transferase PGst Class-PiGstp1-1 |
| Database Links | Reactome: R-HSA-156590Reactome: R-HSA-3299685Reactome: R-HSA-6798695Reactome: R-HSA-9753281 |
| Cellular Localisation | CytoplasmMitochondrionNucleusThe 83 N-Terminal Amino Acids Function As Un Uncleaved Transit PeptideAnd Arginine Residues Within It Are Crucial For Mitochondrial Localization |
| Alternative Protein Names | Glutathione S-Transferase P proteinGst Class-Pi proteinGstp1-1 proteinGSTP1 proteinFAEES3 proteinGST3 protein |
Information sourced from Uniprot.org