Human Glutathione S-transferase mu 3/GSTM3 protein (Recombinant) (His-Tag) (STJP017586)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human Glutathione S-transferase mu 3/GSTM3-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE/Enzyme Activity |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% Glycerol, 0.1M NaCl |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Immunoreactivity | Specific activity is > 15, 000pmol/min/ug, and is defined as the amount of enzyme that conjugate 1.0 u mole of 1-chloro-2, 4-dinitrobenzene (CDNB) with reduced glutathione per minute at pH 6.5 at 25C. |
Target Information
| Gene Symbol | GSTM3 |
| Gene ID | 2947 |
| Uniprot ID | GSTM3_HUMAN |
| Accession Number | NP_000840 |
| Immunogen | Human |
| Immunogen Region | 1-225aa |
| Immunogen Sequence | MGSSHHHHHH SSGLVPRGSH MGSHMSCESS MVLGYWDIRG LAHAIRLLLE FTDTSYEEKR YTCGEAPDYD RSQWLDVKFK LDLDFPNLPY LLDGKNKITQ SNAILRYIAR KHNMCGETEE EKIRVDIIEN QVMDFRTQLI RLCYSSDHEK LKPQYLEELP GQLKQFSMFL GKFSWFAGEK LTFVDFLTYD ILDQNRIFDP KCLDEFPNLK AFMCRFEALE KIAAYLQS |
Additional Info
| Tissue Specificity | Testis and brain. |
| Post Translational Modifications | The N-terminus is blocked. |
| Function | Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. May govern uptake and detoxification of both endogenous compounds and xenobiotics at the testis and brain blood barriers. |
| Protein Name | Glutathione S-Transferase Mu 3Gst Class-Mu 3Gstm3-3Hgstm3-3 |
| Database Links | Reactome: R-HSA-156590 |
| Cellular Localisation | Cytoplasm |
| Alternative Protein Names | Glutathione S-Transferase Mu 3 proteinGst Class-Mu 3 proteinGstm3-3 proteinHgstm3-3 proteinGSTM3 proteinGST5 protein |
Information sourced from Uniprot.org