Human Glutathione S-transferase alpha 4/GSTA4 protein (Recombinant) (His-Tag) (STJP019203)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human Glutathione S-transferase alpha 4/GSTA4-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE/Enzyme Activity |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) 2mM DTT, 20% Glycerol, 100mM NaCl |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Immunoreactivity | Specific activity is > 4, 000pmol/min/ug, and is defined as the amount of enzyme that conjugate 1.0 u mole of 1-chloro-2, 4-dinitrobenzene (CDNB) with reduced glutathione per minute at pH 6.5 at 25C. |
Target Information
| Gene Symbol | GSTA4 |
| Gene ID | 2941 |
| Uniprot ID | GSTA4_HUMAN |
| Accession Number | NP_001503 |
| Immunogen | Human |
| Immunogen Region | 1-222aa |
| Immunogen Sequence | MGSSHHHHHH SSGLVPRGSH MGSHMAARPK LHYPNGRGRM ESVRWVLAAA GVEFDEEFLE TKEQLYKLQD GNHLLFQQVP MVEIDGMKLV QTRSILHYIA DKHNLFGKNL KERTLIDMYV EGTLDLLELL IMHPFLKPDD QQKEVVNMAQ KAIIRYFPVF EKILRGHGQS FLVGNQLSLA DVILLQTILA LEEKIPNILS AFPFLQEYTV KLSNIPTIKR FLEPGSKK |
Additional Info
| Tissue Specificity | Expressed at a high level in brain, placenta, and skeletal muscle and much lower in lung and liver. |
| Function | Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. This isozyme has a high catalytic efficiency with 4-hydroxyalkenals such as 4-hydroxynonenal (4-HNE). |
| Protein Name | Glutathione S-Transferase A4Gst Class-Alpha Member 4Glutathione S-Transferase A4-4 |
| Database Links | Reactome: R-HSA-156590 |
| Cellular Localisation | Cytoplasm |
| Alternative Protein Names | Glutathione S-Transferase A4 proteinGst Class-Alpha Member 4 proteinGlutathione S-Transferase A4-4 proteinGSTA4 protein |
Information sourced from Uniprot.org