Human Glutathione peroxidase 7/GPX7 protein (Recombinant) (His-Tag) (STJP017514)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human Glutathione peroxidase 7/GPX7-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 20% Glycerol, 0.1M NaCl, 1mM DTT |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | GPX7 |
| Gene ID | 2882 |
| Uniprot ID | GPX7_HUMAN |
| Accession Number | NP_056511 |
| Immunogen | Human |
| Immunogen Region | 20-187aa |
| Immunogen Sequence |
Additional Info
| Tissue Specificity | Expressed in esophageal epithelial cells.expression is up-regulated after exposure to acidic bile acids. |
| Function | It protects esophageal epithelia from hydrogen peroxide-induced oxidative stress. It suppresses acidic bile acid-induced reactive oxygen species (ROS) and protects against oxidative DNA damage and double-strand breaks. |
| Protein Name | Glutathione Peroxidase 7Gpx-7Gshpx-7Cl683 |
| Database Links | Reactome: R-HSA-3299685 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Glutathione Peroxidase 7 proteinGpx-7 proteinGshpx-7 proteinCl683 proteinGPX7 proteinGPX6 proteinUNQ469 proteinPRO828 protein |
Information sourced from Uniprot.org