Human Glutathione Peroxidase 2/GPX2 (U40C) protein (Recombinant) (His-Tag) (STJP017449)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human Glutathione Peroxidase 2/GPX2 (U40C)-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.25 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 7.5) containing 40% Glycerol, 0.15M NaCl, 1mM DTT |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | GPX2 |
| Gene ID | 2877 |
| Uniprot ID | GPX2_HUMAN |
| Accession Number | NP_002074 |
| Immunogen | Human |
| Immunogen Region | 1-190aa |
| Immunogen Sequence | MGSSHHHHHH SSGLVPRGSH MAFIAKSFYD LSAISLDGEK VDFNTFRGRA VLIENVASLC GTTTRDFTQL NELQCRFPRR LVVLGFPCNQ FGHQENCQNE EILNSLKYVR PGGGYQPTFT LVQKCEVNGQ NEHPVFAYLK DKLPYPYDDP FSLMTDPKLI IWSPVRRSDV AWNFEKFLIG PEGEPFRRYS RTFPTINIEP DIKRLLKVAI |
Additional Info
| Tissue Specificity | Mostly in liver and gastrointestinal tract, not found in heart or kidney. |
| Function | Catalyzes the reduction of hydroperoxides in a glutathione-dependent manner thus regulating cellular redox homeostasis. Can reduce small soluble hydroperoxides such as H2O2, cumene hydroperoxide and tert-butyl hydroperoxide, as well as several fatty acid-derived hydroperoxides. Cannot reduce phosphatidycholine hydroperoxide. |
| Protein Name | Glutathione Peroxidase 2Gpx-2Gshpx-2Gastrointestinal Glutathione PeroxidaseGlutathione Peroxidase-GastrointestinalGpx-GiGshpx-GiGlutathione Peroxidase-Related Protein 2Gprp-2Phospholipid Hydroperoxide Glutathione Peroxidase Gpx2 |
| Database Links | Reactome: R-HSA-2142688Reactome: R-HSA-2142712Reactome: R-HSA-2142770Reactome: R-HSA-3299685Reactome: R-HSA-5628897 |
| Cellular Localisation | CytoplasmCytosol |
| Alternative Protein Names | Glutathione Peroxidase 2 proteinGpx-2 proteinGshpx-2 proteinGastrointestinal Glutathione Peroxidase proteinGlutathione Peroxidase-Gastrointestinal proteinGpx-Gi proteinGshpx-Gi proteinGlutathione Peroxidase-Related Protein 2 proteinGprp-2 proteinPhospholipid Hydroperoxide Glutathione Peroxidase Gpx2 proteinGPX2 protein |
Information sourced from Uniprot.org