Human GLRX3 protein (Recombinant) (N-His) (STJP003396)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human GLRX3-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | GLRX3 |
| Gene ID | 10539 |
| Uniprot ID | GLRX3_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Val10-Ser117 |
Additional Info
| Function | Together with BOLA2, acts as a cytosolic iron-sulfur (Fe-S) cluster assembly factor that facilitates 2Fe-2S cluster insertion into a subset of cytosolic proteins. Acts as a critical negative regulator of cardiac hypertrophy and a positive inotropic regulator. Required for hemoglobin maturation. Does not possess any thyoredoxin activity since it lacks the conserved motif that is essential for catalytic activity. |
| Protein Name | Glutaredoxin-3Pkc-Interacting Cousin Of ThioredoxinPicotPkc-Theta-Interacting ProteinPkcq-Interacting ProteinThioredoxin-Like Protein 2 |
| Database Links | Reactome: R-HSA-917937 |
| Cellular Localisation | CytoplasmCytosolCell CortexMyofibrilSarcomereZ LineUnder The Plasma MembraneAfter Pma StimulationGlrx3 And Prkcq/Pkc-Theta Translocate To A More Extended Submembrane AreaIn The Z LineFound Associated With Csrp3 |
| Alternative Protein Names | Glutaredoxin-3 proteinPkc-Interacting Cousin Of Thioredoxin proteinPicot proteinPkc-Theta-Interacting Protein proteinPkcq-Interacting Protein proteinThioredoxin-Like Protein 2 proteinGLRX3 proteinPICOT proteinTXNL2 proteinHUSSY-22 protein |
Information sourced from Uniprot.org