Human GLB1 protein (Recombinant) (C-His) (STJP013207)

SPECIFICATIONS
HostMammalian Cells
ConjugationUnconjugated
ImmunogenHomo sapiens (Human)
STJP013207-100
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General Information

Short DescriptionRecombinant-Human GLB1-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications.
ApplicationsELISA/WB
HostMammalian Cells
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ConjugationUnconjugated
FormulationSupplied as a 0.22 Mu m filtered solution in 20mM Tris-HCl, 150mM NaCl, pH 8.0.
Storage InstructionUse a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin< 1 EU/µg as determined by LAL test.

Target Information

Gene SymbolGLB1
Gene ID2720
Uniprot IDBGAL_HUMAN
ImmunogenHomo sapiens (Human)
Immunogen RegionLeu24-Val677

Additional Info

Function Isoform 1: Cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans. Isoform 2: Has no beta-galactosidase catalytic activity, but plays functional roles in the formation of extracellular elastic fibers (elastogenesis) and in the development of connective tissue. Seems to be identical to the elastin-binding protein (EBP), a major component of the non-integrin cell surface receptor expressed on fibroblasts, smooth muscle cells, chondroblasts, leukocytes, and certain cancer cell types. In elastin producing cells, associates with tropoelastin intracellularly and functions as a recycling molecular chaperone which facilitates the secretions of tropoelastin and its assembly into elastic fibers.
Protein Name Beta-Galactosidase
Acid Beta-Galactosidase
Lactase
Elastin Receptor 1
Database Links Reactome: R-HSA-2022857
Reactome: R-HSA-2024096
Reactome: R-HSA-2206308
Reactome: R-HSA-4085001
Reactome: R-HSA-4341670
Reactome: R-HSA-6798695
Reactome: R-HSA-9840310
Cellular Localisation Isoform 1: Lysosome
Isoform 2: Cytoplasm
Perinuclear Region
Localized To The Perinuclear Area Of The Cytoplasm But Not To Lysosomes
Alternative Protein Names Beta-Galactosidase protein
Acid Beta-Galactosidase protein
Lactase protein
Elastin Receptor 1 protein
GLB1 protein
ELNR1 protein

Information sourced from Uniprot.org

Citations

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