Human GITR (Glucocorticoid Induced Tumor Necrosis Factor Receptor) Sandwich ELISA Kit (STJE0009174)
SPECIFICATIONS
General Information
| Short Description | This GITR Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human serum, plasma, tissue homogenates, cell lysates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Human |
| Sensitivity | 5.9pg/mL |
| Detection Limit | 15.6-1000pg/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 4.5 hrs |
Target Information
| Gene Symbol | TNFRSF18 |
| Gene ID | 8784 |
| Uniprot ID | TNR18_HUMAN |
| Sample Type | serum, plasma, tissue homogenates, cell lysates or other biological fluids. |
Additional Info
| Tissue Specificity | Expressed in lymph node, peripheral blood leukocytes and weakly in spleen. |
| Post Translational Modifications | |
| Function | Receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway. |
| Protein Name | Tumor Necrosis Factor Receptor Superfamily Member 18Activation-Inducible Tnfr Family ReceptorGlucocorticoid-Induced Tnfr-Related ProteinCd Antigen Cd357 |
| Database Links | Reactome: R-HSA-5669034Reactome: R-HSA-8877330 |
| Cellular Localisation | Isoform 1: Cell MembraneSingle-Pass Type I Membrane ProteinIsoform 2: Secreted |
| Alternative ELISA Names | Tumor Necrosis Factor Receptor Superfamily Member 18 ELISA kitActivation-Inducible Tnfr Family Receptor ELISA kitGlucocorticoid-Induced Tnfr-Related Protein ELISA kitCd Antigen Cd357 ELISA kitTNFRSF18 ELISA kitAITR ELISA kitGITR ELISA kitUNQ319 ELISA kitPRO364 ELISA kit |
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Information sourced from Uniprot.org