Human GFPT1 protein (Recombinant) (His-Tag) (STJP018873)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human GFPT1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 50% Glycerol, 2mM DTT, 2mM EDTA |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | GFPT1 |
| Gene ID | 2673 |
| Uniprot ID | GFPT1_HUMAN |
| Accession Number | NP_001231639 |
| Immunogen | Human |
| Immunogen Region | 332-699aa |
| Immunogen Sequence |
Additional Info
| Tissue Specificity | Isoform 1 is predominantly expressed in skeletal muscle. Not expressed in brain. Seems to be selectively expressed in striated muscle. |
| Function | Controls the flux of glucose into the hexosamine pathway. Most likely involved in regulating the availability of precursors for N- and O-linked glycosylation of proteins. Regulates the circadian expression of clock genes BMAL1 and CRY1. Has a role in fine tuning the metabolic fluctuations of cytosolic UDP-GlcNAc and its effects on hyaluronan synthesis that occur during tissue remodeling. |
| Protein Name | Glutamine--Fructose-6-Phosphate Aminotransferase Isomerizing 1D-Fructose-6-Phosphate Amidotransferase 1Glutamine -Fructose-6-Phosphate Amidotransferase 1Gfat 1Gfat1Hexosephosphate Aminotransferase 1 |
| Database Links | Reactome: R-HSA-381038Reactome: R-HSA-4085023Reactome: R-HSA-446210 |
| Cellular Localisation | |
| Alternative Protein Names | Glutamine--Fructose-6-Phosphate Aminotransferase Isomerizing 1 proteinD-Fructose-6-Phosphate Amidotransferase 1 proteinGlutamine -Fructose-6-Phosphate Amidotransferase 1 proteinGfat 1 proteinGfat1 proteinHexosephosphate Aminotransferase 1 proteinGFPT1 proteinGFAT proteinGFPT protein |
Information sourced from Uniprot.org