Function | GDP-dissociation inhibitor preventing the GDP to GTP exchange of most Rab proteins. By keeping these small GTPases in their inactive GDP-bound form regulates intracellular membrane trafficking. Negatively regulates protein transport to the cilium and ciliogenesis through the inhibition of RAB8A. |
Protein Name | Rab Gdp Dissociation Inhibitor BetaRab Gdi BetaGuanosine Diphosphate Dissociation Inhibitor 2Gdi-2 |
Database Links | Reactome: R-HSA-6798695Reactome: R-HSA-8876198 |
Cellular Localisation | CytoplasmMembranePeripheral Membrane Protein |
Alternative Protein Names | Rab Gdp Dissociation Inhibitor Beta proteinRab Gdi Beta proteinGuanosine Diphosphate Dissociation Inhibitor 2 proteinGdi-2 proteinGDI2 proteinRABGDIB protein |
Information sourced from Uniprot.org