Human GDI2 protein (Recombinant) (His-Tag) (STJP018750)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human GDI2-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.5 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% Glycerol, 1mM DTT |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | GDI2 |
| Gene ID | 2665 |
| Uniprot ID | GDIB_HUMAN |
| Accession Number | NP_001485 |
| Immunogen | Human |
| Immunogen Region | 1-445aa |
| Immunogen Sequence | MGSSHHHHHH SSGLVPRGSH MGSMNEEYDV IVLGTGLTEC ILSGIMSVNG KKVLHMDRNP YYGGESASIT PLEDLYKRFK IPGSPPESMG RGRDWNVDLI PKFLMANGQL VKMLLYTEVT RYLDFKVTEG SFVYKGGKIY KVPSTEAEAL ASSLMGLFEK RRFRKFLVYV ANFDEKDPRT FEGIDPKKTT MRDVYKKFDL GQDVIDFTGH ALALYRTDDY LDQPCYET |
Additional Info
| Tissue Specificity | Ubiquitous. |
| Function | GDP-dissociation inhibitor preventing the GDP to GTP exchange of most Rab proteins. By keeping these small GTPases in their inactive GDP-bound form regulates intracellular membrane trafficking. Negatively regulates protein transport to the cilium and ciliogenesis through the inhibition of RAB8A. |
| Protein Name | Rab Gdp Dissociation Inhibitor BetaRab Gdi BetaGuanosine Diphosphate Dissociation Inhibitor 2Gdi-2 |
| Database Links | Reactome: R-HSA-6798695Reactome: R-HSA-8876198 |
| Cellular Localisation | CytoplasmMembranePeripheral Membrane ProteinGolgi ApparatusTrans-Golgi Network |
| Alternative Protein Names | Rab Gdp Dissociation Inhibitor Beta proteinRab Gdi Beta proteinGuanosine Diphosphate Dissociation Inhibitor 2 proteinGdi-2 proteinGDI2 proteinRABGDIB protein |
Information sourced from Uniprot.org