Human GDI1 protein (Recombinant) (His-Tag) (STJP018785)

SPECIFICATIONS
HostE.coli
ImmunogenHuman
STJP018785
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General Information

Short DescriptionRecombinant-Human GDI1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
ApplicationsSDS-PAGE
HostE.coli
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

Concentration0.25 mg/mL
FormulationLiquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 20% Glycerol, 1mM DTT
Storage InstructionFor short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolGDI1
Gene ID2664
Uniprot IDGDIA_HUMAN
Accession NumberNP_001484.1
ImmunogenHuman
Immunogen Region1-447aa
Immunogen SequenceMDEEYDV IVLGTGLTEC ILSGIMSVNG KKVLHMDRNP YYGGESSSIT PLEELYKRFQ LLEGPPESMG RGRDWNVDLI PKFLMANGQL VKMLLYTEVT RYLDFKVVEG SFVYKGGKIY KVPSTETEAL ASNLMGMFEK RRFRKFLVFV ANFDENDPKT FEGVDPQTTS MRDVYRKFDL GQDVIDFTGH ALALYRTDDY LDQPCL

Additional Info

Tissue Specificity Brain.predominant in neural and sensory tissues.
Function Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. Promotes the dissociation of GDP-bound Rab proteins from the membrane and inhibits their activation. Promotes the dissociation of RAB1A, RAB3A, RAB5A and RAB10 from membranes.
Protein Name Rab Gdp Dissociation Inhibitor Alpha
Rab Gdi Alpha
Guanosine Diphosphate Dissociation Inhibitor 1
Gdi-1
Oligophrenin-2
Protein Xap-4
Database Links Reactome: R-HSA-8876198
Cellular Localisation Cytoplasm
Golgi Apparatus
Trans-Golgi Network
Alternative Protein Names Rab Gdp Dissociation Inhibitor Alpha protein
Rab Gdi Alpha protein
Guanosine Diphosphate Dissociation Inhibitor 1 protein
Gdi-1 protein
Oligophrenin-2 protein
Protein Xap-4 protein
GDI1 protein
GDIL protein
OPHN2 protein
RABGDIA protein
XAP4 protein

Information sourced from Uniprot.org

Citations

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